E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2023. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-010

Surrogate Marker for Atherosclerosis by Using Coronary Stent Length in ST Elevation Myocardial Infarction (STEMI).

By Mohd Khairi Othman, Siti Aisyah Hussin, Muhammad Zulkifli Bin Konok, Zurkurnai Yusof, W Yus Haniff W Isa

Presenter

Mohd Khairi Othman

Authors

Mohd Khairi Othman1, Siti Aisyah Hussin1, Muhammad Zulkifli Bin Konok1, Zurkurnai Yusof1, W Yus Haniff W Isa1

Affiliation

Hospital Universiti Sains Malaysia, Malaysia1
View Study Report
TCTAP A-010
Acute Coronary Syndromes (STEMI, NSTE-ACS)

Surrogate Marker for Atherosclerosis by Using Coronary Stent Length in ST Elevation Myocardial Infarction (STEMI).

Mohd Khairi Othman1, Siti Aisyah Hussin1, Muhammad Zulkifli Bin Konok1, Zurkurnai Yusof1, W Yus Haniff W Isa1

Hospital Universiti Sains Malaysia, Malaysia1

Background

ST elevation myocardial infarction (STEMI)  is a condition that is endemic  around the globe. It is a major public health concerns and accrued high mortality. Various surrogate markers have been used to assess atherosclerosis severity.      We hypothesize the stent length as one of surrogate markers to reflect atherosclerosis severity.

Methods

This is a retrospective,single-centre study done in teaching hospital; Hospital Universiti Sains Malaysia. The study period was from June 2021 until February 2022.The inclusion criteria was patients with STEMI who underwent pharmacoinvasive strategy. The exclusion criteria acute left main stem occlusion, STEMI Killip 4, a history of cardiac arrest during the same admission and planned for CABG surgery. All data analysed using descriptive analysis and Spearman correlation using SPSS 27.

Results

25 out of 85 patients who fulfilled the criteria were analyzed. Mean patient age was 54 (±12.18) year-old and 88% were male. Regarding comorbidities, hypertension (36.0%), diabetes mellitus (40.0%), dyslipidemia (72.0%), chronic renal failure (4.0%), and previous history of PCI were 4.0%. Mean HbA1c was 9.9 (±13.7)%, and LDL was 4.04 (±1.4)mmol/L. The mean LV ejection fraction (LVEF) was 53.8 (±10.4)%.  The mean length and size of coronary stent was 22.9 (±12.3)mm, 3.14(±0.56)mm and contrast usage was 70 (± 28.3)ml. There was a strongly positive correlation of LDL level with coronary stent length (r=0.76, p= 0.045) on Spearman correlation test. However, there was no significant correlation between length of the coronary stent and HbA1c level.

Conclusion

In this study, our mean age population was similar to the Malaysia national PCI data registry.There was a moderately positive correlation between level of LDL with the coronary stent length. Thus coronary stent length may be use as surrogate marker of severe atherosclerosis. However a larger prospective study should conducted to prove this hypothesis.

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