Abstract

  1. Home
  2. E-Science Station
  3. Abstract
JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2022. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-034

OCEANUS (PrOspective multiCentEr study of cArotid artery steNting Using mer Stent) Study – 30-Day and Five -Year Results

By Przemek Nowakowski, Piotr Odrowaz-Pieniazek

Presenter

Przemek Nowakowski

Authors

Przemek Nowakowski1, Piotr Odrowaz-Pieniazek2

Affiliation

University of Technology, Katowice, Poland1, John Paul II Hospital, Jagiellonian University, Poland2
View Study Report
TCTAP A-034
Carotid & Neurovascular Intervention

OCEANUS (PrOspective multiCentEr study of cArotid artery steNting Using mer Stent) Study – 30-Day and Five -Year Results

Przemek Nowakowski1, Piotr Odrowaz-Pieniazek2

University of Technology, Katowice, Poland1, John Paul II Hospital, Jagiellonian University, Poland2

Background

BackgroundObjective: Technological progress in devices dedicated for carotid artery stenting and hence endovascular interventions brings about continued improvement of treatment results. Introduction of new generation self-expanding, open-cell stents may take this improvement even further. We report 30-day and 5-year clinical outcomes of carotid artery stenting using a new open-cell MER stent in a cohort at higher risk for carotid endarterectomy. The study was registered at ClinicalTrials.gov (NCT03133429). 
 

Methods

Material and Methods: This was a single arm, prospective study involving four high-volume endovascular treatment centres in Poland. One hundred patients entered the study (61 men and 39 women). The mean age was 68.3 +/-8.2; fifty-six patients were asymptomatic. The study protocol required the use of embolic protection devices. The primary endpoint was a stroke within a 30-day follow-up. The secondary endpoints were the 30-day, 1-year and 5-year cumulative incidence of death, stroke and myocardial infarction, 1- and 5-year target vessel revascularization, procedural success (residual stenosis ≤30%), restenosis rate (%DS ≥50%) and Serious Adverse Device Effect (SADE).

Results

Procedure and Results: Predilatation was performed in 45 patients (45%) and distal and proximal protection was used in 81% and 19% respectively. The mean internal carotid artery stenosis rated in QCA before and after stent implantation was 81.98+/-9.15% and 12.52+/-8.70%, respectively (p<0.001. Procedural success rate was 100%. Two ischemic stroke (2%)in symptomatic group was observed (within 30 days and in 4-th year of follow-up). 3% TVR rate was reported (1% in Sx group).Three myocardial infarctions and therteen deaths were reported within five years of the intervention.

Conclusion

Conclusions: the OCEANUS study results confirmed the safety and efficacy of MER stent during 30-day and 5-year follow-ups, both in symptomatic and asymptomatic patients. A further cohort study is planned to assess long-term results.

E-Science Station