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Lots of interesting abstracts and cases were submitted for TCTAP 2025. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP C-169

A Case of LAD CTO With Negative Remodeling. Less Is More!

By Chun Yu Fung

Presenter

Chun Yu Fung

Authors

Chun Yu Fung1

Affiliation

Tuen Mun Hospital, Hong Kong, China1,
View Study Report
TCTAP C-169
Coronary - DES/BRS/DCB

A Case of LAD CTO With Negative Remodeling. Less Is More!

Chun Yu Fung1

Tuen Mun Hospital, Hong Kong, China1,

Clinical Information

Patient initials or Identifier Number

Relevant Clinical History and Physical Exam

A 69-year-old gentleman presented with inferoposterior STEMI Presented with chest pain, no heart failure symptoms 
Primary PCI was activated.LM diffuse disease LAD: mLAD CTO with faint antegrade flow and retrograde from RCALCx: mLCx total occlusion, OM1 severe disease RCA: mRCA ATO Runthrough NS wired to PL under Crosair Pro XSLesion predilated with Ryurei 2.0/15 Xience 3.5/48 deployed at m-dRCA


Relevant Test Results Prior to Catheterization

ECG on admission show STE over inferior and posterior leads with RV involvement  Echo done the following day after PPCI : LVEF 40% by Biplane, Hypokinesia over basal to mid inferior and posterior wall Satisfactory RV systolic function Valves unremarkable
peak CK 4600

Relevant Catheterization Findings

stage PCI was arranged 
L system was similar to PPCI findings 
RCA: TIMI III flow, significant plaque at pRCA and dRCA

Interventional Management

Procedural Step

Stage PCI to RCA with JR4 6Fr GCIVUS: under-expansion of stent, significant plaque distal to stent. Another lesion in pRCA with heavy plaque burden and plaque rupture Lesion prepared with Raiden 4.0/15 and NSE 4.0/13Xience 4.0/8 deployed just distal to old stent Xience 3.5/48 deployed to ostial to mRCAPSHP with Raiden 4.0/15 and Raiden 4.5/10 L system PCI with JL4 7Fr GCPCI to LCxRunthrough wired to OM Lesion predilated with sapphire 2.25/15 and Apollo 3.0/15Xience 2.75/33 deployed at pLCx- OM PSHP with NC Trek Neo 3.5/8 and Apollo 3.0/15  PCI to LAD LAD CTO wired with Fielder XT-A under Corsair Pro XSExchanged back to Runthrough NSSerial dilatation with Sapphire 0.85/10, Sapphire 1.0/15, Sapphire II Pro 1.5/15, Sapphire 2.0/15IVUS: small vessel in dLAD, mLAD bridging, pLAD heavy plaque burden
Consideration for stenting- small vessel size at distal landing, high risk of future ISR- potential positive remodeling in future and stent malapposition - myocardial bridging at mLAD 
Further prepare lesion with Scoreflex 2.5/15, Apollo 3.0/15 DEB to pLAD with Pantera Lux 3.0/25Small dissection in pLAD. TIMI III flow. decided for restudy Coro +/- stenting
Restudy coro after 10 months:LAD: positive remodelling of vessel, TIMI III flow. Dissection healed LCx and RCA: patent stent Plan to continue medical treatment and not for further stenting 


Case Summary

Although the recent REC-CAGEFREE I trial show that drug eluting balloon (DEB) fail to achieve non-inferiority compared with drug eluting stenting (DES) for de novo, non-complex coronary artery disease. DEB still have a role in treating specific condition, such as lesion in small vessels. Our case demonstrate that DEB is useful for CTO lesion with distal vessel negative remodelling. Had a undersized DES been deployed in our case, the risk of stent thrombosis and restenosis will be high.  Our case also demonstrate that minor type B dissection after DEB can be managed conservatively, healing is possible and no stenting is needed if TIMI III flow is preserved.