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TCTAP C-244

Fulminant Myocarditis Complicated With Recurrent Arrhythmia and Bi-Ventricular Failure Survived Under Micro-Axial Flow Catheter Support

By Kuo Hsuan Hung, Chih-Fan Yeh

Presenter

Kuo Hsuan Hung

Authors

Kuo Hsuan Hung1, Chih-Fan Yeh1

Affiliation

National Taiwan University Hospital, Taiwan1,
View Study Report
TCTAP C-244
Heart Failure - Mechanical Circulatory Support

Fulminant Myocarditis Complicated With Recurrent Arrhythmia and Bi-Ventricular Failure Survived Under Micro-Axial Flow Catheter Support

Kuo Hsuan Hung1, Chih-Fan Yeh1

National Taiwan University Hospital, Taiwan1,

Clinical Information

Patient initials or Identifier Number

Relevant Clinical History and Physical Exam

A 24-year-old womanexperienced nausea and abdominal discomfort days before a shortsyncope episode. She was taken to a local hospital. EKG showed sinustachycardia, low QRS voltage, and  ST elevation over aVR, V1-3. CT scan of the brain revealed no signs of intracranial hemorrhage.  Shewas transferred to our hospital under norepinephrine infusion.

Relevant Test Results Prior to Catheterization

At triage, she wasalert but hypotensive. Labs showed elevated troponin-T and NT-pro BNPlevels and leukocytosis. CXR showed perihilarinfiltrates, and TTE indicated mild LVEF reduction and globalhypokinesia of LV. Given the suspicion of fulminant myocarditis, shebegan IVIG therapy.


Relevant Catheterization Findings

Coronary Angiography:
LM: Patent
LAD: Patent
LCX: Patent
RCA: Patent

Hemodynamics:
Cardiac output : Average 2.13 ( L/min ) by thermodilution
RPAW: 19 mmHg
MPA: 28/22 mmHg
RA 26/22 mmHg

Pathology:
Diffuse mononuclear cells with some eosinophils in destructive myocytes.The cells are predominent CD3 positive T cells. Viral myocarditis isfavored.


Interventional Management

Procedural Step

**STEP 1: DiagnosticCAG**Puncturedright EIA; placed 6Fr sheath.EngagedLCA with 5Fr JL4 catheter, showing patent LCA, and with 5Fr JR4 for RCA,showing patent RCA.
**STEP2: Endomyocardial Biopsy**Puncturedright EIV; placed 7Fr sheath.Advancedlong sheath with 6Fr pigtail for RV angiography, localized atmid-septum. Collected 4 biopsy specimens (1 mm©ø each) forhistopathology.
**STEP3: PAC for Hemodynamic Study**InsertedSwan-Ganz catheter to distal RPA.
**STEP 4: Insert ABIOMED Impella CP¢ç Microaxial Flow Catheter for Cardiogenic Shock**  Pre-embedded 2 Abbott Perclose ProGlide¢â  SMC System sutures at right EIA sheath. Inserted Impella sheath; Advanced 0.18 wire to LV with pigtail, and checked Impella CP device for function and primed with saline. Positioned Impella tip in LV using fluoroscopy; removed guidewire and connected to console. Confirmed Impella function; secured access site.
**STEP 5: Removal of Impella on Day 5**  Removed Impella after inserting 0.35 J-tip wire to aorta; Achieved hemostasis using ProGlide¢â sutures.


Case Summary

We report a youngwoman with fulminant myocarditis, who survived with temporary Impella CP¢ç support. An initial ECG showed ST elevation in V1 and aVR, indicatingpossible right ventricular involvement. For circulatory support, wechosed Impella CP¢ç because VA-ECMO would increase afterload, leadingto pulmonary edema and poor LV recovery. Even RV was involved withimpaired RV function, her clinical condition remained stable underthe treatment guided by PAC. By day 3, her cardiac function hadimproved much, and the Impella CP¢ç was removed on day 5. The patient wasdischarged on day 11. One-month follow-up showed full RV and LVrecovery.