E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2025. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-040

Drug-Coated Balloon Versus Drug-Eluting Stent Revascularization in the Treatment of De Novo Acute Myocardial Infarction

By Ae-Young Her, Yong Hoon Kim, Eun-Seok Shin

Presenter

Ae-Young Her

Authors

Ae-Young Her1, Yong Hoon Kim1, Eun-Seok Shin2

Affiliation

Kangwon National University, Korea (Republic of)1, Ulsan University Hospital, Korea (Republic of)2
View Study Report
TCTAP A-040
DES/BRS/DCB

Drug-Coated Balloon Versus Drug-Eluting Stent Revascularization in the Treatment of De Novo Acute Myocardial Infarction

Ae-Young Her1, Yong Hoon Kim1, Eun-Seok Shin2

Kangwon National University, Korea (Republic of)1, Ulsan University Hospital, Korea (Republic of)2

Background

BACKGROUND: Data on DCB (drug-coated balloon)-only treatment inthe context of AMI (acute myocardial infarction) are limited. We investigated to assess the efficacy and safety of a DCB treatment on percutaneous coronary intervension in patietns with de novo AMI.

Methods

METHODS A total of 96 patients with de novoAMI successfully treated with DCB alone were retrospectively enrolled. Visualresidual stenosis ¡Â 30% without flow-limiting dissection was considered asatisfactory pre-balloon angioplasty and followed by DCB treatment. We comparedit with 96 propensity-matched patients treated with second-generation drug-elutingstent (DES) from the PTRG-DES registry (n = 13,160 patients). Major adversecardiovascular events (MACE) comprised cardiac death, myocardial infarction,stroke, stent or target lesion thrombosis, target vessel revascularization, andmajor bleeding (Bleeding Academic Research Consortium bleeding type 3 orgreater) at 1 year.

Results

RESULTS Baseline clinical characteristicswere comparable between the groups. The mean device diameter was larger in DESgroup (2.7 ¡¾ 0.3 mm vs. 3.1 ¡¾ 0.4 mm, P < 0.001). No abrupt vessel closurerequiring treatment occurred after treatment with DCB. The MACE was comparablein both groups (6.2% in DCB group vs. 7.3% in DES group, P = 0.301) at 1-yearfollow-up.

Conclusion

CONCLUSIONS In de novo AMI patients,DCB-only treatment approach had comparable clinical outcomes at 1-yearfollow-up. DCB-only treatment may be a safe and effective alternative to DES incarefully selected patients who had satisfactory pre-dilation results.