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Lots of interesting abstracts and cases were submitted for TCTAP 2025. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-004

Regional Variations in Sex-Based Outcomes of Transcatheter Aortic Valve Replacement: A Meta-Analysis of 657,850 Patients

By Sofian Zreigh, Ahmad Al Othman, Mohammed Benhammou, Abubaker Salahudin Mukhlif Al-Allawee, Walid Guerguer, Ashraf Haidarah, Serag Almzainy, Qasim Ezeddin Shawesh, Saber Khalid, Mohamedhen Vall Nounou, Rafeeek Elmezayen, Mohammad Alzu’bi, Maram Abuajamieh, Muhiddin Drvis, Muhammed Elhadi

Presenter

Sofian Zreigh

Authors

Sofian Zreigh1, Ahmad Al Othman2, Mohammed Benhammou3, Abubaker Salahudin Mukhlif Al-Allawee4, Walid Guerguer5, Ashraf Haidarah6, Serag Almzainy7, Qasim Ezeddin Shawesh7, Saber Khalid8, Mohamedhen Vall Nounou9, Rafeeek Elmezayen10, Mohammad Alzu’bi11, Maram Abuajamieh12, Muhiddin Drvis1, Muhammed Elhadi7

Affiliation

Ankara Yildirim Beyazit University, Turkey1, Near East University, Cyprus2, University of Oran 1, Algeria3, University of Fallujah, Iraq4, University of Algiers 1, Algeria5, West China Hospital, China6, University of Tripoli, Libya7, Benghazi University, Libya8, University of Nouakchott Al Aasriya, Mauritania9, Kafr-Elsheikh University, Egypt10, The Hashemite University, Jordan11, Cairo University, Egypt12
View Study Report
TCTAP A-004
Complex TAVR

Regional Variations in Sex-Based Outcomes of Transcatheter Aortic Valve Replacement: A Meta-Analysis of 657,850 Patients

Sofian Zreigh1, Ahmad Al Othman2, Mohammed Benhammou3, Abubaker Salahudin Mukhlif Al-Allawee4, Walid Guerguer5, Ashraf Haidarah6, Serag Almzainy7, Qasim Ezeddin Shawesh7, Saber Khalid8, Mohamedhen Vall Nounou9, Rafeeek Elmezayen10, Mohammad Alzu’bi11, Maram Abuajamieh12, Muhiddin Drvis1, Muhammed Elhadi7

Ankara Yildirim Beyazit University, Turkey1, Near East University, Cyprus2, University of Oran 1, Algeria3, University of Fallujah, Iraq4, University of Algiers 1, Algeria5, West China Hospital, China6, University of Tripoli, Libya7, Benghazi University, Libya8, University of Nouakchott Al Aasriya, Mauritania9, Kafr-Elsheikh University, Egypt10, The Hashemite University, Jordan11, Cairo University, Egypt12

Background

Aortic stenosis (AS) is a common valvular heart disease, with an estimated prevalence ranging from 3% to 10%, affecting females and males equally. Transcatheter aortic valve replacement (TAVR) has emerged as a widely adopted treatment in AS, demonstrating efficacy across various risk profiles. However, the impact of sex differences on TAVR outcomes remains a topic of debate, with a notable gap in literature addressing these variations across diverse geographical regions. This meta-analysis seeks to investigate sex-based differences in TAVR outcomes and evaluate their consistency across regions.

Methods

A comprehensive literature search was conducted across Scopus, Cochrane Library, PubMed, and Web of Science databases up to October 2024. Studies comparing TAVR outcomes between males and females were included and grouped by region based on available data: Europe, Asia, and North America. A random-effects meta-analysis was performed to calculate the risk ratio (RR) and mean differences (MD) with 95% confidence intervals (CI) for the outcomes, and heterogeneity was assessed using the I² statistic. Statistical analysis was conducted using R Studio version 4.3.2 with the 'meta' package.

Results

The results and conclusions of the BEST CLINICAL ABSTRACTS will be released after the presentation on April 25.

Conclusion

The results and conclusions of the BEST CLINICAL ABSTRACTS will be released after the presentation on April 25.

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