Lots of interesting abstracts and cases were submitted for TCTAP 2025. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!
TCTAP A-054
Prognostic Impact of Coronary CT Angiography-Detected High-Risk Plaques on Patients After Stenting for Integrated Backscatter IVUS-Identified Thin-Cap Fibro Atheroma (TCFA)
By Masaya Ohta, Hideki Kawai, Masato Ishikawa, Hideaki Oota, Takashi Muramatsu, Yukio Ozaki, Hideo Izawa
Presenter
Masaya Ohta
Authors
Masaya Ohta1, Hideki Kawai2, Masato Ishikawa2, Hideaki Oota2, Takashi Muramatsu2, Yukio Ozaki1, Hideo Izawa2
Affiliation
Fujita Health University Okakzaki Medical Center, Japan1, Fujita Health University Hospital, Japan2
View Study Report
TCTAP A-054
Invasive Imaging (IVUS, OCT, NIRS, VH, etc)
Prognostic Impact of Coronary CT Angiography-Detected High-Risk Plaques on Patients After Stenting for Integrated Backscatter IVUS-Identified Thin-Cap Fibro Atheroma (TCFA)
Masaya Ohta1, Hideki Kawai2, Masato Ishikawa2, Hideaki Oota2, Takashi Muramatsu2, Yukio Ozaki1, Hideo Izawa2
Fujita Health University Okakzaki Medical Center, Japan1, Fujita Health University Hospital, Japan2
Background
While patients after stenting for lipid rich plaque were at increased risk of cardiovascular events as previously reported, it has not yet been investigated whether high-risk plaque on coronary CT angiography in these patients was a surrogate marker of ischemic events. We therefore sought to examine the association of major adverse cardiovascular event (MACE) in patients after stenting for integrated backscatter-intravascular ultrasound (IVUS)-identified thin-cap fibro atheroma (TCFA) with high-risk plaques on coronary CT angiography in the non-culprit lesion.
Methods
From May 2010 to October 2017, a total of 100 consecutive patients with acute coronary syndrome (ACS) and chronic coronary syndrome (CCS) which were performed coronary CT angiography within three months before or after percutaneous coronary intervention (PCI), were enrolled in this study. Based on our previous study, integrated backscatter IVUS identified-TCFA was detected as a combination of lipid core abutting lumen, percentage of lipid area>53.6, and remodeling index >1.03, high risk plaque on coronary CT angiography was defined as plaque with plaque rupture and/or low attenuated plaque (<30HU). The primary endpoint was defined as a MACE (a composite of cardiovascular death, non-fatal myocardial infarction, any revascularization).
Results
During a median follow up of four years, MACEs were observed in 37 patients (37%). The incidences of the MACEs were higher in patients after stenting for integrated backscatter IVUS identified-TCFA with high-risk plaques than in those without both integrated backscatter IVUS identified-TCFA and high-risk plaque (log lank p<0.01). Additionally, after adjustment of confounding factors, the combination of integrated backscatter IVUS identified-TCFA and high-risk plaque (HR 2.72; 95% CI: 1.35-5.46; p<0.01) were the independent predictors for the MACE as well as prior PCI (hazard ratio [HR] 2.43; 95% confidence interval [CI]: 1.11-4.1; p=0.02).
Conclusion
We concluded that high-risk plaque on coronary CT angiography in patients after stenting for integrated backscatter IVUS identified-TCFA may be a novel marker for MACE after successful PCI.