Lots of interesting abstracts and cases were submitted for TCTAP 2025. Below are the accepted ones after a thorough review by our official reviewers. Don’t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!
TCTAP A-041
Midterm Cardiovascular Outcomes After Paclitaxel-Coated Balloon Angioplasty Versus Drug-Eluting Stent Placement for Coronary Large Vessel: A Meta-Analysis
By Yoshihiro Mera
Presenter
Yoshihiro Mera
Authors
Yoshihiro Mera1
Affiliation
Dokkyo Medical University, Japan1
View Study Report
TCTAP A-041
DES/BRS/DCB
Midterm Cardiovascular Outcomes After Paclitaxel-Coated Balloon Angioplasty Versus Drug-Eluting Stent Placement for Coronary Large Vessel: A Meta-Analysis
Yoshihiro Mera1
Dokkyo Medical University, Japan1
Background
We conducted a systematic review and meta-analysis to examine the feasibility of paclitaxel-coated balloon (PCB) angioplasty for de novo lesions in coronary large vessel (LV) bycomparing with drug-eluting stent (DES) placement.
Methods
By a systematic literature search, four (one randomized controlled, one retrospectivepropensity-score matched, and two retrospective applying multivariate Cox proportionalhazard) studies comparing the midterm cardiovascular outcomes after PCB angioplasty andDES placement were included, providing 175 and 547 cases in PCB and DES groups,respectively. The primary evaluation (PE) item was the primary endpoints of four studiescomposite of cardiac mortality, myocardial infarction, target vessel revascularization, targetlesion revascularization, or all-cause mortality. Risk ratio (RR) and hazard ratio (HR) forcomparisons of PE between PCB angioplasty and DES placement in LV were examined by arandom-effect model.
Results
The frequencies of MACE in PCB and DES groups were 7.2% and 13.1%, respectively. PCBangioplasty had no significant impacts on PE after 12 months from index PCI with RR of 0.54(95%CI: 0.25-1.19, p = 0.127) by four studies Figure).
Conclusion
The present systematic review and meta-analysis showed the feasibility of PCB angioplastyfor de novo lesions in coronary large vessels in comparison with recent DES placemen.