E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2024. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-062

Optical Coherence Tomography-Guided or Intravascular Ultrasound-Guided PCI for True Bifurcation Lesions in the OCTIVUS Trial

By Seongbong Wee, Do-Yoon Kang, Duk-Woo Park, Seung-Jung Park

Presenter

Seongbong Wee

Authors

Seongbong Wee1, Do-Yoon Kang1, Duk-Woo Park1, Seung-Jung Park1

Affiliation

Asan Medical Center, Korea (Republic of)1
View Study Report
TCTAP A-062
Bifurcation

Optical Coherence Tomography-Guided or Intravascular Ultrasound-Guided PCI for True Bifurcation Lesions in the OCTIVUS Trial

Seongbong Wee1, Do-Yoon Kang1, Duk-Woo Park1, Seung-Jung Park1

Asan Medical Center, Korea (Republic of)1

Background

This study compared the effectiveness and safety of optical coherence tomography (OCT)-guided vs. intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) for true bifurcation coronary-artery lesions.

Methods

This was a pre-specified, main subgroup analysis of true bifurcation coronary-artery lesions in the OCTIVUS trial. The primary end-point was a composite of death from cardiac causes, target-vessel-related myocardial infarction, or ischemia-driven target-vessel revascularization. Crude and adjusted analyses using inverse-probability-of-treatment weighting (IPTW) and overlap propensity-score weighting were performed.

Results

In 2008 randomized patients, 428 (21.3%) underwent imaging-guided PCI for true bifurcation coronary-artery lesions; 185 (43.2%) received OCT-guided PCI and 243 (56.8%) received IVUS-guided PCI. At a median follow-up of 2.0 years (available for at least 1 year and up to 4.8 years), primary end-point event had occurred in 20 (10.8%) patients in the OCT-guided group and in 18 (7.4%) patients in the IVUS-guided group (hazard ratio [HR] 1.32; 95% confidence interval [CI] 0.69–2.52; P=0.40). The incidence of contrast-induced nephropathy was similar between the OCT-guided and the IVUS-guided groups (1.1% vs. 2.1%, respectively; P=1.00).

Conclusion

Among patients with true bifurcation coronary-artery lesions, OCT-guided PCI showed a similar risk of primary-composite event of death from cardiac causes, target-vessel–related myocardial infarction, or target-vessel revascularization as compared with IVUS-guided PCI.