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April 26 (Thu.), 2012
TCTAP 2012 Late Breaking Clinical Trials
VARC Outcomes Following TAVI with Both Edwards SAPIENTM and Medtronic CoreValve ReValving System Devices: 30-Days and One-Year Results from the Milan Registry
The aim of this study was to assess clinical outcomes following transcatheter
aortic valve implantation (TAVI) according to the Valve Academic Research Consortium (VARC) definitions in our single center experience.
In total, 400 consecutive patients with severe symptomatic aortic stenosis underwent TAVI in the San Raffaele Scientific Institute, Milan, Italy from Nov. 2007 to Feb. 2012 utilizing either Edwards SAPIENTM/SAPIEN XTTM or Medtronic CoreValve ReValving System devices, since they were commercially available in
Europe. The overall mean age was 79.4 ¡¾ 7.4 years, logistic.......
Dr. Martin B. Leon Awarded The 2nd TCTAP Award
'Master of the Masters'

Dr. Martin B. Leon, director of Center for Interventional Vascular Therapy, Columbia University Medical Center / New York-Presbyterian Hospital, was recognized as the 2nd recipient of TCTAP Award ‘Master of the Masters’, held on April 25 (Wed) at the Main Arena(Vista hall), the convention center of Sheraton Grand Walkerhill hotel. CardioVascular Research Foundation (CVRF), organizing committee of ANGIOPLASTY SUMMIT-TCTAP has held an award ‘Master of the Masters’ during TCTAP since 2011 and Dr. Masakiyo Nobuyoshi, director of Kokura Memorial Hospital, was honored as the 1st recipient of this award last year. TCTAP Award ‘Master of the Masters’ is bestowed to honor and show appreciation to outstanding teachers and dedicators in the field of interventional cardiology. Especially TCTAP has been benefited from Dr. Leon’s outstanding expertise and value enabling this meeting more special. Therefore, the organizing committee has generously agreed to nominate him to this award.......

FFR Guided and IVUS Supported Functional Angioplasty in Left Main Coronary Artery Disease
In this TCTAP 2012 meeting, Seung-Jung Park, MD from Asan Medical Center, Seoul, Korea summarized the concept of optimal treatment of left main coronary artery disease: FFR guided and IVUS Supported Functional Angioplasty in Left Main Coronary Artery Disease.
Significant narrowing of the left main coronary artery puts a patient at high risk, since it can jeopardize the entire myocardium of the left ventricle, and it has the worst prognosis of any form of coronary artery disease. Therefore, for several decades, based on clinical trials for comparing coronary-artery bypass grafting (CABG) with medical therapy, bypass surgery has been regarded as the treatment of choice for patients with unprotected left main coronary artery (LMCA) disease. However, recently, marked advancements in techniques of percutaneous coronary intervention (PCI) and adjuvant pharmacologic therapy make a new evaluation of the optimal revascularization therapy for LMCA disease.......
The State of the Art Lecture; Wrap-Up and Brand-New Knowledge with Expert
Periprocedural Antithrombotic Therapy During PCI- Lessons from ISAR-REACT 1, 2, 3, 4, Trials
Adnan Kastrati, MD (Deutsches Herzzentrum, Technische Universitat, Munich, Germany) will give a lecture about periprocedural antithrombotic therapy during PCI with the
results of the ISAR-REACT trial. He focused on the results of ISAR-REACT 4, which was recently published in the New England Journal of Medicine. The direct thrombin inhibitor bivalirudin protects patients with NSTEMI from severe adverse events as well as a combination of abciximab and unfractionated heparin following PCI while reducing major bleeding. The data suggests that bivalirudin might be the preferred drug for patients undergoing PCI for an acute MI, with or without ST-segment elevation. They studied 1,721 patients with NSTEMI who had been pre-treated with 600 mg of clopidogrel prior to PCI. Patients were randomized to 70 U/kg bolus of heparin plus abciximab in a 0.25 mg/kg bolus.......
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