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ABS20200325_0001
| Stents (bare-metal, drug-eluting) | |
| Real World Application of 2 MM Drug Eluting Stents: A Single-Center Experience | |
| Chih Hung Lai1, Chi-Yao Huang1, Chieh-Shou Su1, Wei-Chun Chang1, Tsun-Jui Liu1, Szu-Ling Chang1, Wen-Lieng Lee2 | |
| Taichung Veterans General Hospital, Taiwan1, Taichung VGH, Taiwan2 | |
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Background:
There is limited real-world data on optimal treatment ofcoronary artery stenosis in very small coronary vessels. Small 2 mm drugeluting stents (DES) are now commercially available. The clinical outcomes ofsmall vessel stenting with current generation 2 mm DES have not been fullyelucidated.
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Methods:
There is limited real-world data on optimal treatment ofcoronary artery stenosis in very small coronary vessels. Small 2 mm drugeluting stents (DES) are now commercially available. The clinical outcomes ofsmall vessel stenting with current generation 2 mm DES have not been fullyelucidated.
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Results:
A total 115 patients with 148 stents (Resolute Onyx: 140,Xience Alpine: 7) implanted were analyzed. The median age was 66 years.Patients with heart failure and diabetes mellitus consisted of 20.9% and 57.4%of the study population respectively, and 23.5% presented with acute myocardialinfarction. Majority of the treated lesions were complex (ACC/AHA type B2/C:85.8%, chronic total occlusion lesion: 23%, moderate or severecalcification:61.5%). The mean reference vessel diameter was 2.05 ¡¾ 0.08 mm.The mean lesion length was 21.69 ¡¾ 6.23 mm, and the mean number of stentsimplanted per patient were 1.25 ¡¾ 0.6. Intra-vascular imaging was used in 12.2%of the patients. The post-stenting minimal lumen diameter was 2.08 ¡¾ 0.09. Theprocedure success rate was 98.6%. Total 114 patients were followed up formean twenty months (mean: 595 days) and TLF and TLR at twenty months is 7.9%and 4.4% respectively. The primary end point of TLF at one-year was 5.4%. Ratesof cardiac mortality, target vessel myocardial infarction and TLR were 2.2%,1.1% and 3.3%, respectively at one-year. No definite/probable stent thrombosisdeveloped during whole follow-up (Table 1).
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Conclusion:
Our real world outcomes of 2 mm DES wasassociated with a low rate of TLF and TLR, without a signal for stentthrombosis. These novel-sized drug-eluting stents appears a good safety andefficacy and could be a feasible option for the treatment of coronary lesionsin extremely small vessels.
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