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ABS20191115_0002
| Other (Unclassified) | |
| Efficacy of Low Glycemic Diet to Improve Triglycerides and Glycated Hemoglobin in Patients with Atherosclerotic Coronary Artery Disease | |
| Bakhrom Alyavi1, Jamol Uzokov Jamol Uzokov2, Djamshid Payziev1 | |
| Republican Specialized Scientific-Practical Medical Center, Uzbekistan1, Republican specialized scientific practical medical center of therapy and medical rehabilitation, Uzbekistan2 | |
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Background:
Dyslipidemia is common among diabetic patients and one of the main causes of atherosclerotic cardiovascular disease (ASCVD). Aim of this study was to estimate the efficacy of low glycemic diet on triglycerides and glycated hemoglobin (HbA1c) in patients with ASCVD.
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Methods:
This study was conducted from 2016 June till2019 January enrolling with 156 patients (male=49; aged 38-75 years; mean age57.6¡¾11.8 years ;) with diagnosed ASCVD. The patients divided into two groups by 78. In the first group, patients were assigned low glycemic diet and in second (control) group patients were advised to continue their routine diet during the 3 months on the background of standard therapy. Laboratory and instrumental data were obtained at baseline and after the 12weeks of the intervention.
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Results:
There were no statistically differences in biochemical data between two groups at their baseline characteristics. Low glycemic diet had a positive impact on triglyceride in the first group than controls (from 245.6¡¾37.3 mg/dL to 159.2¡¾25.6 mg/dL vs. from226.9¡¾34.8 mg/dL to 192.1¡¾26.5 mg/dL; P<0.05). HbA1c also decreased significantly in the first intervention group patients than second group (from 6.9¡¾1.9 % to 4.8¡¾1.2 % vs.6.7¡¾1.6 % to 6.2¡¾1.4%; P<0.05).
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Conclusion:
Low glycemic diet is superior to routine diet to reduce triglycerides and HbA1c in patients with atherosclerotic cardiovascular disease. Further studies are needed to clarify with large amount of participants.
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