Lots of interesting abstracts and cases were submitted for TCTAP & AP VALVES 2020 Virtual. Below are accepted ones after thoroughly reviewed by our official reviewers. Don¡¯t miss the opportunity to explore your knowledge and interact with authors as well as virtual participants by sharing your opinion!
* The E-Science Station is well-optimized for PC.
We highly recommend you use a desktop computer or laptop to browse E-posters.
ABS20191028_0010
| Peripheral Vascular Disease and Intervention | |
| Pressure Wire-Guided Endovascular Therapy Reduces the Total Dose of Paclitaxel Applied to Patients with Diffuse Tandem Lesion of the Superficial Artery | |
| Shigeyasu Tsuda1 | |
| Kita-Harima Medical Center, Japan1 | |
|
Background:
Among patients with stable coronary artery disease, evaluation of functional ischemia using pressure wire (PW) is effective. In contrast, in patients with superficialartery (SFA), there is little evidence of ischemic assessment for endovasculartherapy (EVT).It has been demonstrated that Drug-coated balloon (DCB) technologies reduce restenosis and the need for reintervention compared with percutaneous transluminal angioplasty. However, one paper reported the association of a late mortality signal with the use of DCB, namely paclitaxel.
|
|
|
Methods:
We hypothesized that PW-guided EVT would be superior to angiography (AG)-guided EVT in patients withSFA diffuse tandem lesion in evaluating functional ischemia and reducing the total dose of paclitaxel applied.Among 24 patients with angiographically diffuse tandem lesion of the SFA, 12 patients each were treated by PW-guided EVT and AG-guided EVT, respectively. There was no significant difference between the two groups in the pre-treatment ankle-brachial pressure index (0.61vs. 0.57; P=0.569).In the AG-guided EVT, DCB was used in the angiographically stenotic lesion after pre-dilatation. In the PW-guided EVT group, only the stenotic sites that had pressure gradients > 10mmHg we retreated with DCB after pre-dilatation.
|
|
|
Results:
The amount of DCB was lower in the group treated with PW-EVT compared with the AG-EVT group (1 vs. 1.33; P<0.05). The total length of the DCB was significantly lower in the PW-EVT group compared with the AG-EVT group (82.5mm vs. 160mm; P<0.05).Furthermore, the total dose of paclitaxel applied was significantly lower in the PW group (4.6mg vs. 8.8mg;P<0.05).Post-treatment ABI showed no significant difference between the two groups (0.99 vs. 0.96).
|
|
|
Conclusion:
In patients with diffusetandem lesion of the SFA, PW-guided EVT can reduce the amount of balloon, the total length of balloon dilatation and a total dose of paclitaxel applied.
|
|
0