E-Science Station

It has been suggested that ABO blood group is a risk factor for atherosclerotic cardiovascular disease (ASCVD), which is also associated with the incident of cardiovascular events (CVE) in patients with of ASCVD. However, the role of ABO blood group in prediction of CVE in patients with myocardial infarction (MI) has not been determined. The aim of this study was to examine the association between ABO blood groups and the cardiovascular death in patients with MI.

A total of 2051 patients with MI enrolled consecutively in this analysis. ABO blood and their baseline characteristics, the number of disease vessels assessed by coronary angiography, and ABO blood group were collected. And then all patients were subjected to follow-up.

The median follow-up was 28.83 ± 15.38 months, and 33 death (1.61 %) was detected. The higher percentage of abnormal low-density lipoprotein cholesterol and the number of diseased vessels were found in patients with A blood group compared with that in ones with non-A blood groups. Moreover, Cox regression analysis revealed that A blood group (OR: 2.255, 95% CI: 1.132 - 4.494 , p = 0.021) was demonstrated to be independent predictors of cardiovascular mortality. During the follow-up period, Kaplan-Meier analysis according to the mortality revealed a higher occurrence of mortality in A blood group compared to that with non-A blood group (p = 0.047).

The present data firstly indicated that A blood group was indeed associated with cardiovascular mortality in patients with MI.