E-Abstract

JACC

Lots of interesting abstracts and cases were submitted for TCTAP 2023. Below are the accepted ones after a thorough review by our official reviewers. Don¡¯t miss the opportunity to expand your knowledge and interact with authors as well as virtual participants by sharing your opinion in the comment section!

TCTAP A-068

Use of FFR in Chronic Stable Angina Patients and Its Impact on PCI and In-Hospital Outcome

By Smita Kanungo, Fazila Malik, Nazir Ahmed, Mohammad Badiuzzaman, Ashok Kumar Dutta, Dhiman Banik, Md Kalimuddin, Nazmun Laila, Shamim Chowdhury

Presenter

Smita Kanungo

Authors

Smita Kanungo1, Fazila Malik1, Nazir Ahmed1, Mohammad Badiuzzaman1, Ashok Kumar Dutta1, Dhiman Banik1, Md Kalimuddin1, Nazmun Laila1, Shamim Chowdhury1

Affiliation

National Heart Foundation Hospital & Research Institute, Bangladesh1
View Study Report
TCTAP A-068
Physiologic Lesion Assessment

Use of FFR in Chronic Stable Angina Patients and Its Impact on PCI and In-Hospital Outcome

Smita Kanungo1, Fazila Malik1, Nazir Ahmed1, Mohammad Badiuzzaman1, Ashok Kumar Dutta1, Dhiman Banik1, Md Kalimuddin1, Nazmun Laila1, Shamim Chowdhury1

National Heart Foundation Hospital & Research Institute, Bangladesh1

Background

Background: Coronary artery disease (CAD) is aleading global cause of mortality and morbidity.  Improvements in the diagnosis and treatmentof CAD can reduce the health and economic burden. Fractional flow reserve isevidence based diagnostic test of the physiological significance of a coronaryartery stenosis. PTCA of a coronary stenosis without documented ischemia isoften performed, but its benefit is unproven. Purpose of this study was toobserve the impact on PCI and its in hospital outcome in patients with chronicstable angina in our setting.

Methods

Descriptive type of cross-sectional studyconducted at Department of Cardiology, National Heart Foundation Hospital &Research Institute, Dhaka.  Total 72patients with chronic stable angina were enrolled according to inclusion andexclusion criteria. Patients were divided into two groups. Group I consisted of36 patients underwent PCI without FFR and group II having 36 patients underwentPCI with FFR. Quantitative data expressed as mean and standard deviation andqualitative data as frequency and percentage. 

Results

According tothe study, there was no significant difference regarding coronary arterystenosis in both group (p value 0.073).In group II, fractional flow reserve was <0.80 found in 29 patients. Presentstudy demonstrated that, in Group-I maximum patients 15 (41.6%) were revascularizedby two stents and 11(30.5%) patients required three stents. On the other handGroup-II maximum patients 17(47.2%) required single stent, 9(25.0%) patientstreated by two stents, 3(8.3%) patients received three stent and medicalmanagement was given to 7(19.4%) patients. This study also revealed that FFRgroup needed significantly less number of stent (73 in Group -I and 44 in Groupll p value is .002). However, comparison of in hospital outcome in terms ofMACCE and other complications demonstrated that there was no significantdifference between two groups.

Conclusion

: FFR guided PCI was associated with the less PCI,implantation of fewer stents thus cost effective. It also aided for preciserevascularization decision and thus reduced the burden of PCI. But  FFR guided angioplasty did not have anysignificant impact on its  in hospitaloutcome.